The American, who was supplanted as Spurs' No.1 by the Frenchman during the 2012-13 season, does not believe that his old team-mate is looking to leave White Hart Lane despite his stated desire to play Champions League football.
Lloris has been linked with United as a potential successor to David de Gea, courted by Real Madrid, but the Red Devils have already signed Sergio Romero this summer and Friedel is unconcerned about the 28-year-old's future.
"For me, personally, I don't foresee that transfer even remotely starting up," he told the Daily Express.
"Hugo is a Tottenham player, he is the Tottenham captain and he will be a Tottenham player and I don't see that changing. I don't even think we need to discuss that possibility and I mean that sincerely."
De Gea's future at Old Trafford continues to lack a clear resolution but, though acknowledging that players not getting a transfer that they wanted can unsettle teams, Friedel believes that he could yet stay at United without causing trouble.
"It's completely down to the player and his attitude," he explained.
"From my limited experience playing against David de Gea and speaking to him briefly after games, he seems like a really good guy and, if the transfer deadline comes and goes and he stays a Manchester United player, I think they will both be fine.
"But if there is a bit of petulance involved in the player - and by no means am I suggesting that David de Gea is like this - it can absolutely affect things. It can affect the changing room, it can affect personal performances, it can affect a whole host of things.
"Sometimes it is a little bit turbulent up until that deadline day and then, once that comes and goes and the player is still at the club, then I'm afraid he just has to get on with it.
"You might even see him sign a new contract at Manchester United."
