Louis van Gaal, who suggested the Spain international was not focused enough to feature amid a prolonged stand-off with Real Madrid over a summer transfer.
But this has not prevented Van Gaal from including his star goalkeeper in his plans for the two-legged tussle with the Belgian giants, sparking fresh optimism around Old Trafford that De Gea could yet stay in Manchester.
De Gea is in the final year of his contract at Old Trafford and has already told United that he wants to join Madrid, but the two clubs are yet to agree a fee and Van Gaal is determined not to let one of his best players leave easily.
MANCHESTER UNITED SQUAD IN FULL
Goalkeepers: David De Gea, Anders Lindegaard, Sergio Romero, Sam Johnstone
Defenders: Phil Jones, Marcos Rojo, Jonny Evans, Chris Smalling, Luke Shaw, Paddy McNair, Matteo Darmian, Tyler Blackett
Midfielders: Adnan Januzaj, Michael Carrick, Daley Blind, Ashley Young, Ander Herrera, Antonio Valencia, Marouane Fellaini, Morgan Schneiderlin, Bastian Schweinsteiger, Jesse Lingard, Andreas Pereira, Memphis Depay, Juan Mata
Strikers: Wayne Rooney, Javier Hernandez, James Wilson.